F2 and hyperlipidemia: For the mask DWI, 27 selected radiomics features (Supplementary Table 8), 12 selected clinical features (age, smoking history, history of hyperlipidaemia, SAP, SBP at the first diagnosis, OCSP type, admission GCS score, 7-d NIHSSmax, prothrombin time, D-dimer, serum troponin I, blood glucose) and 2 selected radiological features (ADC1CV, Grad1CV) were included in the model.