By inferring the Decipher prognostic gene signature in the prostate cancer dataset (GSE116918), differences in fibroblast cells (Fig. 2B), androgen receptor (AR; Fig. 2C), and MYC proto-oncogene (MYC; Fig. 2D) TF activity between the two patient subgroups are observed. This evidence concerns the gene TF and Familial prostate cancer.