As IFN‐γ is a potent anti‐tumor cytokine, we investigated whether STING activation enhanced γδ T cell‐mediated anti‐tumor immunity.[30] We have previously demonstrated the critical role of the Vγ4 subsets of the mouse γδ T cells in γδ T cell‐mediated tumor killing through IFN‐γ.[31] Therefore, we first compared the tumor‐killing capacity of STING‐activated Vγ4 γδ T cells with that of vehicle‐treated cells in vitro and found a markedly higher killing ability in the former than in the latter (Figure S1A,B, Supporting Information). Here, IFNG is linked to neoplasm.