Gamma delta (γδ) T lymphocytes represent a unique cell subset that is crucial in tumor immunity.[1] We previously demonstrated that γδ T cells are essential as an early source of interferon‐gamma (IFN‐γ), a potent cytokine with anti‐tumor properties.[2] Moreover, activated human Vδ2 γδ T cells have shown promising clinical efficacy against lung and liver cancers,[3] highlighting their potential for cancer immunotherapy. This evidence concerns the gene IFNG and cancer.