CCAAT‐enhancer‐binding protein (C/EBPβ), an inflammation‐regulated transcription factor, acts as a key age‐dependent effector elevating both AEP and inflammatory cytokines expression in mediating pathogenesis in PD mouse models.[26] We found the expression levels of C/EBPβ in ALDH1A1 221–501 or both expressed brains robustly increase, consistent with the expression of active AEP. This evidence concerns the gene CEBPB and Parkinson disease.