ALDH1A1 oxidizes 3,4‐dihydroxyphenylacetaldehyde (DOPAL), a reactive metabolite of dopamine, to detoxify it.[6] Inhibition of ALDH1A1 and accumulation of DOPAL contribute to PD pathogenesis.[7] Dopaminergic (DA) neurons in the ventral SNpc that express ALDH1A1 are more resistant to degeneration and exhibit fewer α‐Syn aggregates compared to ALDH1A1‐negative DA neurons in the SNpc. The gene discussed is ALDH1A1; the disease is Parkinson disease.