Rare PTVs in three prioritized genes, not established causes of cardiomyopathy, were found to be associated with binary diseases outcomes (MAP3K7 and NEDD4L with DCM) in at least one cohort (Fig. 4b and Supplementary Tables 11 and 12) and with quantitative traits (NEDD4L, MAP3K7 and SSPN) in UKB (Fig. 4b and Supplementary Table 13). This evidence concerns the gene MAP3K7 and cardiomyopathy.