Other notable genes included: the taurine transporter SLC6A6 (locus 20), with existing evidence of taurine deficiency causing feline DCM24; the cardiac-expressed K+ channel KCNIP2, which has been implicated in Brugada syndrome and conduction abnormalities25; RRAS2, where gain of function variants are a cause of Noonan syndrome and accompanying hypertrophic cardiomyopathy26,27; and several genes implicated in myopathy, including CHCHD10 (locus 80) and DMPK (locus 76). This evidence concerns the gene RRAS2 and Noonan syndrome.