This observation could potentially be attributed to the presence of additional CCL5-independent chemotaxis players that contribute to T cell infiltration within the tumor.40 To assess the therapeutic implications of the reduced OT-I T cell infiltration induced by clodronate liposome or CCL5 neutralization antibody, we conducted an analysis of tumor growth inhibition (Fig. 3f). The gene discussed is CCL5; the disease is neoplasm.