used serum samples and RNA profile samples from subjects with AD to identify biomarkers for AD diagnosis and discovered a novel biomarker set that includes enoyl‐coenzyme A hydratase 1, NHL repeat containing 2, homeobox B7, FN1, neuro/glioblastoma‐derived oncogene homolog (avian) transcript variant 2, and solute carrier family 6 (neurotransmitter transporter, GABA), member 13 with high sensitivity and accuracy. This evidence concerns the gene FN1 and Alzheimer disease.