In the study, the authors demonstrated that Cer d18:1/16:0 and HexCer d18:1/18:0 were upregulated, and Cer d16:1/24:0, GM3 d16:1/22:0, GM3 d18:1/16:0, and SM d16:1/22:0 were downregulated in AD cases. Here, CBLN1 is linked to Alzheimer disease.