AD mice displayed higher concentrations of these cytokines than naïve mice (p < 0.05–0.001, Figures 3 and 4l–p), whereas AD+PLX mice exhibited similar concentrations as naïve control mice for all these cytokines in the hippocampus and IL‐1β, IL‐18, MIP1α, and IL‐6 in the cerebral cortex (p > 0.05, Figures 3 and 4l,m,o,p). The gene discussed is IL1B; the disease is Alzheimer disease.