RPS6KA5 and gastric cancer: The expression of H3S10 phosphorylation has been shown to be associated with a more aggressive form of gastric cancer with loco-regional recurrence [35], and it is believe that the STAT3 and mitogen-and stress-activated protein kinase 1 (MSK1) are involved in phosphorylating H3S10 in these aggressive forms of gastric cancer [36].