GPX4 and psoriasis: Based on the z scores of 19 selected canonical psoriasis-associated pathways, K14/Gpx4 showed the strongest correlation to human psoriasis datasets (r = 0.75–0.96), as well as to K5-Stat3C (r = 0.94) and idIL-23 (r = 0.89) models, and weaker correlation to K14-AREG (r = 0.62) and IMQ (r = 0.17–0.56) models (Figure 5F, Supplemental Figure 9, A and B, and Supplemental Table 9).