Moreover, when analyzing different prognostic models of BC, no risk estimates were noted for the different genetic models of TNF-α−308G > A (rs1800629) SNP in response to the poor prognostic model of the luminal B model (ER+vePR+veHer2+ve), very poor prognostic model (triple–ve) or Her2-enriched poor model (ER−vePR−veHer2+ve) in contrast to the good prognostic status luminal A model (ER+vePR+veHer2−ve). This evidence concerns the gene ERBB2 and breast cancer.