Um et al. [26] evaluated the effect of periostin inhibition by an aptamer‐based inhibitor on renal fibrosis under diabetic conditions, and found TGF‐β1 treatment significantly upregulated periostin, fibronectin, and type I collagen mRNA and protein expressions in inner medullary collecting duct cells in vitro. This evidence concerns the gene TGFB1 and renal fibrosis.