This noninvasive approach characterizes tumors, aiding in predicting treatment outcomes, assessing disease characteristics, revealing biological pathways, and informing clinical decisions.16,17 In certain scenarios, radiomic features surpass clinicopathological factors in prognostic determination,18-20 serving as valuable tumor biomarkers for improved classification of IDH-wildtype glioblastoma.21 Here, IDH1 is linked to glioblastoma.