They found that the expression of PDGFA, PDGFD and PDGFRB in the infarcted myocardium were increased after myocardial infarction, whereas PDGFB and PDGFC mRNAs were reduced and protein levels at infarcted myocardium were all significantly reduced in the early stage of myocardial infarction. The gene discussed is PDGFC; the disease is myocardial infarction.