CD4 and ovarian cancer: Currently, immune cells and stromal cells such as Th cells (28) and fibroblasts (29) in breast cancer, fibroblasts in melanoma (30), CD8+ T cells (31), DCs (32) in lung cancer, and macrophages (33), CD4+ T cells, and DCs (17) in ovarian cancer have all been reported as potential LTo cells that secrete homeostatic chemokines.