BDNF and autism: The sex differences of intrinsic excitability of pyramidal neurons in the PFC of male and female BDNF+/Met mice may partially contribute to the severe autism-like behavioral deficits in male BDNF+/Met mice (Ma et al., 2023) and support that males are more vulnerable to having ASD (Giarelli et al., 2010; Werling and Geschwind, 2013).