Interestingly, in the case of the other prominent loci (both on chromosome 6), the regional and PheWAS views (rs2844697 near SFTA2, rs3763321 near HLA-DRA, and rs9273368 near HLA-DQB1) clearly indicate that these loci exhibit associations with celiac disease and intestinal malabsorption (non-celiac). The gene discussed is HLA-DQB1; the disease is celiac disease.