NLRP3 and colitis: In NLRP3‐ or apoptosis‐associated speck‐like protein containing a CARD (ASC)‐deficient mice, the overgrowth of Prevotellaceae is associated with severe dextran sodium sulfate (DSS)‐induced colitis, likely due to decreased IL‐18 production, which compromises immune defense and epithelial integrity, worsening inflammation and disrupting pyroptosis regulation.