In another CLP‐induced sepsis model, fecal microbiota transplantation and SCFA treatment led to a reduction in Firmicutes and an increase in Proteobacteria and Escherichia‐Shigella, accompanied by downregulation of NLRP3, GSDMD‐N, and IL‐1β.151. This evidence concerns the gene NLRP3 and Sepsis.