Mutations in the SCN1A gene are known to cause autosomal dominant Dravet syndrome (MIM 607208), non-Dravet developmental and epileptic encephalopathy (MIM 619317), familial febrile seizures (MIM 604403), familial hemiplegic migraine (MIM 609634), and generalized epilepsy with febrile seizures (MIM 604403). This evidence concerns the gene SCN1A and Generalized epilepsy with febrile seizures-plus.