Chen et al. found through gene expression profiling analysis using the Cancer Genome Atlas (TCGA) that the risk signal of P4HA1 related genes in CRC consists of 11 genes, including MIR210HG, solute carrier family 4 member 7 (SLC4A7), cell division cycle associated 2 (CDCA2), death associated protein kinase 1 (DAPK1), homeobox C6 (HOXC6), Troponin T 1 (TNNT1), UL16 binding protein 2 (ULBP2), serine protease inhibitor clade E member 1 (SERPINE1), WFDC21P, and forkhead box D1 (FOXD1) (Chen et al., 2021). The gene discussed is CDCA2; the disease is colorectal carcinoma.