ABCB1 and epilepsy: • MEs: dose error, solvent error, wrong route of administration and incorrect infusion time• DDIs: CYP450 enzyme, P-glycoprotein, monoamine oxidase inhibitors, others (such as valproic acid and carbapenem), the establishment of a dedicated DDI knowledge base is highly recommended• ADEs: abnormal laboratory examination, emerging clinical symptoms (such as fever, epilepsy and arrhythmology)