Accordingly, it is of interest that the acceleration of gastric emptying induced by hypoglycemia is attenuated by administration of native GLP-1 (110) and the short-acting GLP-1RA, exenatide (111), which may well increase the potential for a mismatch between nutrient delivery after meal ingestion and insulin action in people co-prescribed a GLP-1RA and insulin, thus predisposing to hypoglycemia. This evidence concerns the gene INS and Hypoglycemia.