In addition, hMDM infection with S. epidermidis 1457 after TLR9 inhibition led to a significantly increased, strong induction of IL1B expression compared to the untreated control, being similar compared to IL1B expression induced after infection of untreated hMDM with S. epidermidis 1457-M10 and 1457ΔatlE, respectively (Fig. 6B). The gene discussed is TLR9; the disease is infection.