This revealed that induction of CML led to a significant survival extension in ANXA2-deficient compared to WT recipient mice (Supplementary Fig. 5A, B), but homing of CML-initiating cells to WT or ANXA2-deficient environments did not differ (Supplementary Fig. 5C). Here, ANXA2 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.