In addition, these tumor cells upregulated fetal liver markers (e.g., SPINK1, GPC3, REG3A, and RELN)14,24–27, and expressed multiple imprinted genes, including IGF2, PEG3, PEG10, DLK1, and MEG3(Fig. 1b and Supplementary Fig. 1c), with DLK1 and MEG3 being located on the 14q32 locus, as previously described by Cairo et al.14 and Carrillo-Reixach et al.20. The gene discussed is IGF2; the disease is neoplasm.