However, when re-challenge was performed in either Kuramochi or A2780 mice, tumor rejection occurred in the NKG2D/Dap10-12 (5/7 Kuramochi and 7/7 A2780 mice) but not the NKG2D-CD3ζ group (0 of 3 A2780 mice; Figures 4B and 4C). The gene discussed is KLRK1; the disease is neoplasm.