Second, in line with previous reports,24,25 R and SI differed in their associations to plasma biomarkers: the plasma concentrations of IFNγ, CXCL10, and CXCL11 proteins in sepsis were mainly correlated with R levels of PBMCs (Pearson’s r = 0.46, 0.47, 0.21, p < 10−5, 10−5, 0.07, respectively), whereas plasma concentrations of IL-6 and IL-18bp were mainly correlated with SI levels of PBMCs (Pearson’s r = 0.71, 0.34, p < 10−15, 10−3) (cf. Figures 1B and S1F). The gene discussed is IFNG; the disease is Sepsis.