Among individual variables, the following were associated with longer time to VS: male sex; age below 50 years; Black and Brown, race/skin color; education ≤11 years of schooling; therapeutic regimen 2NRTI + 1NNRTI; authorized special regimens or unauthorized regimens; initial CD4 count <500 cells/mm3; initial VL >100,000 copies/mL; active tuberculosis episode; therapeutic regimen change; and treatment adherence <95%. The gene discussed is MLC1; the disease is tuberculosis.