(5) A mouse monoclonal antibody MC1 (IgG1) has been identified as a conformation‐specific anti‐tau antibody that decorates globular oligomers as well as longer filamentous tau aggregates by morphological evaluations; however, the detailed characterization of its target molecule species including molecular size has not been disclosed well26, 60 except dot blot study of fractionated AD brain lysate by SDGC,43 where all kinds of tau oligomers species as well as fibrils (from Fr. The gene discussed is MAPT; the disease is Alzheimer disease.