We believe that this is because endogenous IGF2BP2 is highly expressed in cancer cells such as the Huh7.5 cells used here and is presumably not limiting for viral replication in this system (Cui et al., 2021; Feng et al., 2022; Liu et al., 2023a; Pu et al., 2020; Zhang et al., 2024). Here, IGF2BP2 is linked to cancer.