EZH2 assumes an oncogenic role in a range of cancers, including solid tumors like breast cancer [32], prostate cancer [33], esophageal cancer [34], gastric cancer [35], anaplastic thyroid carcinoma [36], and endometrial carcinoma [37] as well as in hematologic malignancies [38] including follicular lymphoma [39]. This evidence concerns the gene EZH2 and Familial prostate cancer.