MKI67 and neoplasm: To further characterize the effects of PDLIM1 knockdown on cell proliferation and survival in the tumor tissues, we performed Hematoxylin and eosin (H&E) staining, immunohistochemical staining for Ki-67 (a well-established proliferation marker), and terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick end labeling (TUNEL) for apoptotic event evaluation.