Through interaction with different proteins within diverse tissues, PDLIM1 exerts its functions in a tissue-specific manner.3 Furthermore, PDLIM1 has been implicated in a variety of signal transduction pathways affecting cell growth and migration during cancer occurrence and development.3 In corroboration with previous studies, our research demonstrated that PDLIM1 has a critical effect on DLBCL cell growth and survival. The gene discussed is PDLIM1; the disease is diffuse large B-cell lymphoma.