In addition, the researchers also confirmed that the use of MLN3651 or knocking down DCAF1 can lead to the loss of activity of KSR1 protein in meningioma cells, which in turn lead to the inactivation of the Raf/MEK/ERK pathway, inhibiting the proliferation of meningioma cells (Lyons Rimmer et al., 2020). This evidence concerns the gene DCAF1 and meningioma.