In addition, the researchers also confirmed that the use of MLN3651 or knocking down DCAF1 can lead to the loss of activity of KSR1 protein in meningioma cells, which in turn lead to the inactivation of the Raf/MEK/ERK pathway, inhibiting the proliferation of meningioma cells (Lyons Rimmer et al., 2020). Here, MAP2K7 is linked to meningioma.