MUC2 and malignant colon neoplasm: Only the Amuc_1434 DUF6268 domain-containing protein of A. muciniphila is able to promote adhesion to the LS174T (colon cancer) cell line, which expresses high levels of MUC2, demonstrating the ability of this bacterium to bind MUC2 in the mouse colon (Meng et al., 2020).