IL4 and Alzheimer disease: Increased inflammatory cell infiltration is observed in AD lesions, including T cells, dendritic cells, macrophages, mast cells, and eosinophils (3).These often precipitate increased cytokines including thymic stromal lymphopoietin (TSLP), interleukin-1 (IL-1), IL-4, IL-5, IL-6, IL-25, IL-33, and transforming growth factor-β (TGF-β), which promote inflammation and immune activation.