As shown in Figure 1d, CRP‐MCM induced the phosphorylation of both the Ser727 and Tyr705 sites on STAT3 in both cell lines; the CRP‐MCM‐induced phosphorylation of the Tyr705 site was stronger than that of the Ser727 site, thereby suggesting that unknown factors contained in CRP‐MCM enhance STAT3 activation and tumor proliferation. The gene discussed is STAT3; the disease is neoplasm.