CD8A and neoplasm: Thus, as shown in Figure 2, compared with non‐dHGP, dHGP metastases displayed statistically significant higher values (adjusted p < 0.05) for all of the three parameters, particularly in the stroma compartment, and even in the tumor compartment for the CD8+/Calprotectin+ ratio, reinforcing the concept that nondesmoplastic metastases displayed a potent immunosuppressive environment.