All resulting heterodimers showed binding specificity,cellular retention, and affinity, while among them [125I]I-PSMA-617-PEG2-triazolyl-Tyr-PEG2-RM26 presentedthe highest values regarding cancer cell uptake and higher tumor accumulation(PC-3, 4.3% ID/g, PC-3 PiP 10% ID/g at 1 h pi). Here, FOLH1 is linked to neoplasm.