Further analyses of a HCC tissue microarray [2] from a Singapore HCC cohort confirmed that ACSL4 expression was present in approximately 60% of primary HCC tissues (Fig. 1b-c) and was associated with poorer overall survival in HCC patients (P = 0.015, Fig. 1d and P = 0.043, Fig. S2a). Here, ACSL4 is linked to hepatocellular carcinoma.