Of particular interest, the expression of 6 genes (VSIG4, LAMP1, QPCT, C1QB, TNFSF13, and JUN) can be used to distinguish the transcriptomic signature of a dormant infection from an uninfected joint replacement (Fig. 6B) highlighting the potential for these markers in diagnosing a dormant infection. Here, TNFSF13 is linked to infection.