In the small sub-set of the participants with isolated PBMCs available, we also found a significant difference in the gene expression levels of CD14, with significantly higher levels in the participants with established CHD or significant stenosis on CTCA compared to the participants with normal arteries or non-significant stenosis, median 3.8 RQ (IQR 3.1–5.9) versus median 0.9 RQ (IQR 0.6–1.4). The gene discussed is CD14; the disease is coronary artery disorder.