ANXA2 and neoplasm: Of note, the GEPIA database indicates, although not significantly, that high ANXA2 mRNA expression is associated with better survival of PCa patients comparing low expression and high expression data plotted against overall survival (Fig. 2D) being in line with previous reports (Ding et al 2010; Grewal et al. 2021) that suggest higher expression level of ANXA2 have tumor suppressive function in PCa.