ACTB and amyotrophic lateral sclerosis: In addition, KEGG analysis indicated the involvement of apoptotic pathways, including “platinum drug resistance,” “hepatocellular carcinoma,” “thyroid hormone signaling pathway,” and “amyotrophic lateral sclerosis” (Fig. 1C), as highlighted by the decreased expression of A0A0S2Z3C5 (BCL2L1) and P60709 (ACTB) (Fig. 1D).