The highest increase in mRNA levels was detected for Sgsm1, which is a modulator of small G‐protein signaling, predicted to be involved in regulation of transcription by RNA polymerase II.[26] Importantly, reduced SGSM1 expression was linked to metastasis in nasopharyngeal carcinoma[27] and was correlated with poor overall survival in gliomas, indicating SGSM1 anti‐oncogenic functions.[26]. This evidence concerns the gene RAC2 and central nervous system cancer.