BAG3 and cancer: Impairment of BAG3’s specific function to clear disease-related aggregate-prone proteins through chaperone-assisted selective autophagy (CASA) was implicated in various diseases, including age-related disorders such as Alzheimer’s disease (Lei et al, 2015), Huntington’s disease (Carra et al, 2008; Fuchs et al, 2009), cancer (De Marco et al, 2018; Kirk et al, 2021), and (cardio-)myopathies (Kimura et al, 2021; Qu et al, 2022).