This variant is found 11kb downstream from CDKN2B-AS1 (cyclin-dependent kinase inhibitor 2B antisense RNA 1) in the CDKN2B-CDKN2A gene cluster on chromosome 9, a significant locus for genetic susceptibility to cardiovascular disease, type 2 diabetes mellitus, and cancer [21]. The gene discussed is CDKN2A; the disease is cardiovascular disorder.