HMGB1 and central nervous system cancer: A similar analysis (Figure 1D and Supplemental Table 2) using a public mRNA-Seq dataset of CCGA glioma patients (19) demonstrated that C3 (necroptosishiapoptosislo) is associated with a better survival probability compared with C2 (apoptosishinecroptosislo) (Figure 1E and Supplemental Table 2), but we observed no significant difference in HMGB1 expression (Figure 1F).