EXOC4 and neurodevelopmental disorder: Defects in the human homologues of yeast SEC5 (corresponding to human EXOC2), SEC6 (EXOC3L2), SEC8 (EXOC4), SEC15 (EXOC6B), EXO70 (EXOC7), EXO84 (EXOC8), and RHO3 (RALA) are associated with a variety of neurodegenerative and neurodevelopmental disorders [212].