Major modifiable risk factors associated with LVR after MI were diabetes (odds ratio [OR] = 2.053, 95% CI: 1.504–2.803), MI site (OR = 2.423, 95% CI: 1.584–3.708), cystatin C (OR = 6.204, 95% CI: 1.830–21.036), B-type natriuretic peptide (OR = 2.280, 95% CI: 1.466–3.546), as well as creatine kinase-myocardial band (OR = 1.013, 95% CI: 0.985–1.042). The gene discussed is CST3; the disease is diabetes mellitus.