Mutations or dysregulation of EPB41L2 have been implicated in various diseases, including cancer and neurological disorders, reflecting its importance in cell function and integrity.[28] Myo1F is expressed in various immune cells including natural killer (NK) cells, macrophages, dendritic cells, and neutrophils.[29] Myo1F is a critical component of the regulation of macrophage function and inflammation. This evidence concerns the gene MYO1F and cancer.